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Our Team

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Principal Investigator

Melissa Lechner, MD, PhD

Dr. Melissa Lechner is a physician-scientist and the Principal Investigator of the research group. She did her MD/PhD in the USC/CalTech program in Los Angeles, then completed residencies in Medicine and Pediatrics in Boston at the Harvard Medical School hospitals. She returned to Los Angeles for her clinical fellowship in Endocrinology and then joined the faculty in 2020. Dr. Lechner’s clinical and research interests are related to autoimmune disease resulting from cancer immunotherapy (checkpoint inhibitors) and novel therapies for advanced thyroid cancer. 

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Staff Research Associate

Kyleigh Kimbrell, BS

Kyleigh moved to Los Angeles from her hometown Noblesville, Indiana motivated by the goal to work in medicine. She recently graduated from UCLA with a degree in microbiology, immunology, and molecular genetics and a minor in disability studies. She wants to continue building on her career in endocrinology and immunology as she is currently applying to medical school. When she is not in the lab, she enjoys exploring California with her family and learning new hobbies.

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Graduate Student

Jarod Olay, MS

Jarod is a graduate student at UCLA in the IMMP PhD program. He graduated from UCSD in 2019 with a degree in Human Biology and a Masters in Biology in 2020. He trained in the Crotty Alexander lab at UCSD, assessing the effects of e-cigarettes in mice. His current works seeks to understand drivers of autoimmune disease like Hashimoto's and type 1 diabetes to improve patient outcomes. In his free time, he is into photography and bike rides.

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UCLA MD/PhD Student

Esther Peluso

Esther is a graduate student and medical student in the UCLA Geffen School of Medicine. Her graduate research seeks to understand mechanisms of immune-related adverse events (IrAEs) as a result of cancer immunotherapy treatment. She is interested in how sex differences and medications that affect central immune tolerance change the severity of IrAEs. 

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Undergraduate Researcher

Joah Lee

Joah is a fourth-year undergraduate student intending to double major in Human Biology and Society and Economics. She hopes to pursue a career in medicine and research. She is interested in autoimmune diseases and tumor immunology. In her free time, Joah loves camping, hiking, and being in the water.

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Undergraduate Researcher

Amber Lu

Amber is a second year undergraduate student majoring in Biochemistry. She is interested in pursuing a career in medicine and research. She studies mechanisms of immune-related adverse events (IrAEs) and enjoys reading and trying new restaurants in her free time.

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Undergraduate Researcher

Ellie Kao

Ellie is a third year undergraduate currently studying at Cal Poly Pomona for chemical engineering & materials science and biotechnology with emphasis on cellular, molecular and microbial biology. She is interested in cancer immunotherapy and autoimmune responses and hopes to enter the medical field as a researcher. While she is not studying, she enjoys her job as an equestrian trainer and rider as San Pascual Stables.

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Undergraduate Researcher

Rachelle Le

Rachelle is recent UCLA graduate who majored in Computational Biology with a specialization in biological data sciences, with plans to pursue graduate school in computational biology and bioinformatics. Her current research involves investigating sex differences in Hashimoto’s Thyroiditis using bioinformatic approaches. In her free time, Rachelle enjoys baking and playing musical instruments.

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Undergraduate Researcher

Jaden Nguyen

Jaden is a recent UCLA graduate majoring in Biology from Huntington Beach, California. He hopes to pursue a career in research and medicine in the future. His current projects include investigating strategies to block checkpoint inhibitor resistance in advanced thyroid cancers. In his free time, you can find him doing photography and trying out new foods.

Alumni

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Natalie Yakobian

Past Staff Research Associate

Current Saint Louis University Medical Student & NIH Visiting Scholar

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Aline Hoang

Past Staff Research Associate

Current Drexel University Medical Student

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Lauren Scott

Past Staff Research Associate

Current Kansas University Medical Student

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Jessica Ortega

Past Staff Research Associate

Current UCSF Medical Student

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Sarah Wang

Past Undergraduate Researcher

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Kristy Kim

Past Medical Student Researcher

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Rana Yakhshi Tafti

Past Researcher

Current Rosalind Franklin Medical Student & NIH Research fellow

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Nicole Huang

Past Researcher

Current UCSF MD/PhD Student

Opportunities

Our lab is seeking collaborative, curious, and highly motivated individuals to join our group.

If you are a graduate student interested in rotating through the Lechner Lab, please email MLechner@mednet.ucla.edu. ​

Graduate students must be admitted to UCLA through one of the PhD degree-granting programs at UCLA. These include the UCLA-Graduate Program in Biosciences (GPB) and the UCLA-Caltech MSTP program among others. Dr. Lechner is a member of the Home Area of Immunity, Microbes, and Molecular Pathogenesis (IMMP) at the UCLA Molecular Biology Institute (MBI). ​

Undergraduate students are welcome in the lab. However, currently, space is limited. Priority will be given to undergraduates who plan to spend a significant amount of time longitudinally in the lab.

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